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KMID : 0361820120310020087
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Journal of the Korean Society of Medical Ultrasound
2012 Volume.31 No. 2 p.87 ~ p.91
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Role of Ultrasound Volume Measurements of Testes in Evaluation of Infertile Men with Azoospermia
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Moon Min-Hoan
Seo Ju-Tae
Chun Yi-Kyeong
Sung Chang-Kyu
Cho Jeong-Yeon
Kim Seung-Hyup
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Abstract
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Purpose: The purpose of our study was to assess the usefulness of ultrasounddetermined testicular volume in the evaluation of the infertile men with azoospermia.
Materials and Methods: A computerized search from October 2005 to June 2010 generated a list of 45 infertile men with azoospermia (mean age, 34 years; age range, 26-44 years) who underwent both scrotal ultrasound and testis biopsy. Ultrasounddetermined testicular volumes were compared between infertile men with obstructive azoospermia and those with non-obstructive azoospermia.
Results: Testicular volume for obstructive azoospermia ranged from 6.4 ml to 26.9 ml, with a median volume of 14.0 ml. This volume was significantly larger than that of those with non-obstructive azoospermia, which ranged from 1.0 ml to 12.8 ml, with a median volume of 6.1 ml (p < 0.001). The area under the ROC curve for distinguishing non-obstructive azoospermia from obstructive azoospermia using testicular volume was 0.91. A cutoff value of less than or equal to 11.4 ml could distinguish non-obstructive azoospermia from obstructive azoospermia, with a sensitivity of 94.1% (95% CI; 71.3-99.9%) and a specificity of 73.3% (95% CI; 54.1-87.7%).
Conclusion: Ultrasound-determined testicular volume can be helpful in the differentiation of obstructive azoospermia from non-obstructive azoospermia.
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KEYWORD
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Ultrasonography, Testis, Azoospermia
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